Correspondence to Wakefield and colleagues case report 2 of 2
- Vaccine Affect
- Apr 4
- 2 min read
Part 2 of 2
Tettenborn agreed with the findings: “The report by Andrew Wakefield and colleagues confirms the clinical observations of several paediatricians, including myself, who have noted an association between the onset of the autistic spectrum and the development of disturbed bowel habit.”
Autism, inflammatory bowel disease, and MMR vaccine
Tettenborn, MA
The Lancet, Volume 351, Issue 9112, 1357
Fisher accused US vaccine policy-makers of inappropriate intervention of politics into what should be an apolitical scientific examination. “Condemning research of the kind undertaken by Wakefield et al will only ensure that no scientific progress is made toward identifying children genetically or otherwise at high risk of immune and neurological dysfunction after vaccination.”
Autism, inflammatory bowel disease, and MMR vaccine
Fisher, Barbara Loe
The Lancet, Volume 351, Issue 9112, 1357 - 1358
Kiln wanted a clarification on which MMR vaccine had been given to these kids as the vaccine that was used in early 1990s had been withdrawn due to adverse reactions to it.
Autism, inflammatory bowel disease, and MMR vaccine
Kiln, MR
The Lancet, Volume 351, Issue 9112, 1358
Roberts commented to another correspondent “Nichol et al considerably understate their case when they write “chance alone dictates that some cases [of autism] will appear shortly after vaccination.” Such a temporal association is unremarkable, given the epidemiology of autism and MMR vaccine.”
MMR vaccination and autism 1998
Roberts
BMJ 1998;316:1824
Andrew Wakefield replies to some of the questions raised
— D R Walker states that “biased selection of patients will influence what you hear”. Bias occurs in science when data are either wittingly or unwittingly concealed. Does he condone the exclusion of a potentially significant element of the history?
— Leonard Sinclair and Peter Richmond and David Goldblatt correctly point out the inappropriate use of adult reference ranges.
These errors do not affect the conclusions of the paper, particularly the identification of ileal lymphoid nodular hyperplasia and colonic inflammation in a group of children with developmental disorder.
— Reply to Rouse - Only one author (AJW) has agreed to help evaluate a small number of these children on behalf of the Legal Aid Board. These children have all been seen expressly on the basis that they were referred through the normal channels (eg, from general practitioner, child psychiatrist, or community paediatrician) on the merits of their symptoms.
No conflict of interest exists.
“The authors stand by their findings. We recommend that paediatric gastroenterologists investigate this problem further, since it is our belief that there is both a large unmet need in the community and a possible window-of opportunity for some children with autism.”
