Is autism a protein defect reversible with natural vitamin A?
- Vaccine Affect

- May 28
- 2 min read
Updated: Jun 2
M.N. Megson
Is autism a G-alpha protein defect reversible with natural vitamin A?
Medical Hypotheses, Volume 54, Issue 6, 2000, Pages 979-983, ISSN 0306-9877,
The DTP vaccine is a vaccine used against diphtheria, tetanus, and pertussis (whooping cough)
In June (2000) Medical Hypotheses published an article by Megson discussing how pertussis toxin (whooping cough) found in the DPT vaccine separates the G-alpha protein from retinoid receptors and how this disruption may be linked to autism. However, only an abstract is available to read.
They also suggest that natural Vitamin A helps to reconnect the retinoid receptors.
“Autism may be a disorder linked to the disruption of the G-alpha protein, affecting retinoid receptors in the brain. A study of 60 autistic children suggests that autism may be caused by inserting a G-alpha protein defect, the pertussis toxin found in the DPT vaccine, into genetically at-risk children. This toxin separates the G-alpha protein from retinoid receptors.”
“Natural vitamin A may reconnect the retinoid receptors critical for vision, sensory perception, language processing and attention.”

Combining vitamin A and vaccines: convenience or conflict?
There is evidence that supports Vitamin A supplementation, when given alongside vaccines, particularly the measles vaccine. It has shown to enhance the immune response and potentially reduce mortality in children.
According to the Benn hypothesis (2012), vitamin A enhances the non-specific beneficial effects on mortality of BCG and measles vaccine, but also enhances the negative effects of DTP vaccine.
“The effect of vitamin A given with DTP vaccine was significantly different from the effect of vitamin A given with measles vaccine, and children, who received vitamin A with DTP vaccine, had higher mortality than children, who had received vitamin A alone, or who did not receive anything.”
“The results also show that boys and girls respond differently to vitamin A and vaccines.”
The existing data as presented by Benn are compatible with the hypothesis that neonatal vitamin A may interact negatively with the subsequent DTP vaccine especially in girls.
“A recent study aiming to develop a live pertussis vaccine have found that a live pertussis vaccine induces a more Th1 deviated response than the inactivated pertussis vaccine. Aluminium based adjuvants used in DTP vaccine induce a Th2 response. Since infants are born with a Th2-deviated immune system, we have speculated that the Th1 inducing effect of the live vaccines may be part of the explanation for their non-specific beneficial effects on overall mortality, whereas the Th2-deviation induced by inactivated vaccines and the aluminium-based adjuvants may be detrimental.”
Benn CS.
Combining vitamin A and vaccines: convenience or conflict?
Dan Med J. 2012 Jan;59(1):B4378. PMID: 22239846.


