Measles in infants born to vaccine-induced mothers
- Vaccine Affect
- Sep 17, 2024
- 1 min read
Updated: Sep 24, 2024
Infants born to mothers with vaccine-induced antibodies lose passive immunity more quickly than infants born to mothers with naturally acquired immunity.
Studies
Multiple studies have found that infants born to vaccinated mothers are more susceptible to measles at a younger age than infants born to mothers who were naturally infected:
An American 1992 study found that 90% of infants born to vaccinated women were susceptible to measles by 7 months, compared to 65% of infants born to mothers who were naturally immune. https://pubmed.ncbi.nlm.nih.gov/1528642/
A 1997 study found that 15% of infants born to vaccinated women were still protected at 8 months, compared to half of infants born to mothers who were naturally immune. https://pubmed.ncbi.nlm.nih.gov/9178461/
In 2000 Klinge et al reported that protection in Germany was shortening over time, leaving almost no infants protected at the age of 9 months. https://pubmed.ncbi.nlm.nih.gov/10856793/
In Switzerland in 2004, 19% of infants still had positive titres after 6-9 months. https://pubmed.ncbi.nlm.nih.gov/15071296/
2006 French study found that 90% of infants are not protected against measles after 6 months of age. https://journals.asm.org/doi/full/10.1128/cvi.00229-08
